A team of Russian researchers has synthesised a previously unknown organic compound based on benzoxazole that both emits fluorescence and inhibits the growth of cancer cells. Laboratory tests have confirmed its cytostatic properties, opening new prospects for the development of molecular tools in cancer diagnostics and targeted therapy. This is reported by the
official website of the Ministry of Science and Higher Education of the Russian Federation.
The compound, identified as 2-(3-(fluorosulfato)phenyl)benzoxazole, combines two key characteristics: the ability to suppress malignant cell division and the capacity to glow under specific conditions. Scientists say this dual functionality could pave the way for real-time monitoring in molecular biology and precision medicine, deepening understanding of drug–cell interactions and enhancing the design of more effective therapies.
Benzoxazole derivatives are already known for their diverse biological activity, including antimicrobial, antiviral and anticancer properties. Their ability to influence cell division makes them promising candidates for the creation of new medicines. The newly synthesised compound demonstrated strong activity in vitro against prostate and breast adenocarcinoma cell lines.
Researchers emphasise that the findings establish a promising basis for the development of novel agents to slow tumour progression and potentially treat malignant diseases.
Future work will focus on exploring the relationship between structure and activity, as well as clarifying the molecular mechanisms underlying the compound’s effects, the source claims.
Photo: Synthetic-Exposition /
iStock
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